Explore Cannabinoids


Delta-9 Tetrahydrocannabinol (Δ9-THC, THC) is the main psychoactive component of plants. Δ9-THC cannabinoids bind to concentrated CB1 cannabinoid receptors in the brain and central nervous system, producing the psychoactive effects. Research shows that delta-9 THC slows down the growth of cancer cells and is more effective when combined with CBD. Other studies have shown that delta-9 THC has therapeutic applications in the gastrointestinal tract and inflammation. It has been found that THC and/or CBD can help reduce the fear memory of PTSD patients.


THCA is the acid form of THC and is non-psychoactive. However, studies have shown that THCA may be a more effective substitute for THC in the treatment of nausea and vomiting. THCA is the cannabinoid precursor of Δ9-THC or Δ8-THC. Through a process called non-enzymatic decarboxylation, which uses a mixture of heat and/or time to remove the carboxyl group from THCA, the compound is converted into the psychoactive compound of Δ9-THC or Δ8-THC. This process is usually done while smoking or vaporizing cannabis products and is also done when manufacturers produce edible or distilled cannabis.


CBD, or cannabidiol, is a non-psychoactive cannabinoid produced by the decarboxylation of CBDA. CBD is a holistic medicine that is popular due to its many health benefits. It is usually related to sedation, which can reduce anxiety. Using CBD alone or in combination with THC can help reduce fear memories in PTSD patients. It can also suppress prostate cancer and regulate the immune system. The World Health Organization (WHO) believes that CBD exhibits no effects indicative of any abuse and is generally well tolerated with a good safety profile.


CBDA, or cannabidiolic acid, is the non-psychoactive cannabinoid precursor of cannabidiol (CBD). Although there has not been much research on the benefits of CBDA, the initial research seems very promising. CBDA is typically consumed through the juicing or consumption of raw cannabis. CBDA may help treat nausea, vomiting, motion sickness or other similar conditions. Studies have shown that it has anti-inflammatory, pain-relieving and anti-cancer effects. When exposed to heat or air to remove carboxyl groups by decarboxylation, CBDA becomes CBD.


CBN, or cannabinol, is a cannabinoid produced by further degradation or decarboxylation of THC. CBN is commonly found in manufactured products, including edible and cannabis distillates, and is usually produced by overheating THC. Although CBN is usually an accidental by-product of the manufacturing process, it is known to have many health benefits. Antibacterial properties are found in CBN and the substance is known to have a sedative effect. CBN can also help regulate the immune system.


Tetrahydrocannabivarin, or THCV, is a cannabinoid typically found only in trace amounts in the cannabis plant. Studies have shown that THCV may reduce inflammatory pain as well as produce an anticonvulsant effect. Some research indicates that THCV can help to regulate blood sugar levels in the human body. Unlike Δ9-THC, THCV is an appetite suppressant, and is therefore beneficial to consumers who are focused on weight loss.


Although delta-8 Tetrahydrocannabinol (Δ8-THC) is a minor component of medicinal cannabis, it has recently become one of the fastest growing segments of hemp derived products. Δ8-THC is often consumed where cannabis is illegal, as an alternative to traditional marijuana use. Δ8-THC is believed to have similar, but less potent, psychoactive effects than Δ9-THC on the consumer.


Cannabidivarin, or CBDV, is a non-psychoactive cannabinoid, similar in structure to CBD. The percentage of CBDV in hemp products is very low, and often non-detectable. Early research indicates that CBDV may be beneficial in reducing epileptic seizures in adults.


Cannabigerol, or CBG, is a non-psychoactive cannabinoid found in low concentrations of the adult cannabis plant. CBG is converted to THC and other cannabinoids during plant growth. Some research suggests that CBG can inhibit the growth of colorectal cancer cells in animals.


Cannabigerolic acid, or CBGA, is often referred to as the mother cannabinoid as it is the precursor molecule for THCA, CBDA, and several other common cannabinoids. Although there is evidence that CBGA may have its own therapeutic uses, most research on the molecule centers around its use in the formation of other cannabinoids.


Cannabichromene, or CBC, is a non-intoxicating cannabinoid, as it has little affinity for the CB1 cannabinoid receptors in the brain. However, CBC binds to other receptors (TRPV1, TRPA1) in the brain releasing many of the body’s natural endocannabinoids. One of these endocannabinoids is anandamide, which has been shown to play a role in eating and sleep patterns as well as pain relief. Anandamide is also shown to inhibit the migration of certain cancer cells.